Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728556 | 0.89 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1NPC1RAB9A | |
| SCHEMBL11848005 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1NPC1RAB9A | |
| SCHEMBL248005 | 0.83 | SMN1; SMN2 (0.43) | ALDH1A1LMNAMAPK1NPC1RAB9A | |
| SCHEMBL287087 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPK1NPC1RAB9A | |
| SCHEMBL11845297 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPK1NPC1RAB9A | |
| SCHEMBL17367390 | 0.81 | PLA2G10 (0.49) | ALDH1A1LMNAMAPK1NPC1RAB9A | |
| SCHEMBL2039904 | 0.80 | SMN1; SMN2 (0.39) | ALDH1A1LMNAMAPK1MAPTGAA | |
| SCHEMBL24745984 | 0.79 | MAPT (0.36) | ALDH1A1LMNAMAPK1NPC1RAB9A | |
| SCHEMBL13267370 | 0.78 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPK1NPC1RAB9A | |
| SCHEMBL9593096 | 0.78 | PLA2G10 (0.39) | ALDH1A1LMNAMAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536205-B2 | Photochromic and electrochromic compounds and synthesis and use thereof | SWITCH MATERIALS INC. (CA) | 2013-09-17 | — | — | US | disclosed |
| US-8536205-B2 | Photochromic and electrochromic compounds and synthesis and use thereof | SWITCH MATERIALS INC. (CA) | 2013-09-17 | — | — | US | disclosed |
| US-8536205-B2 | Photochromic and electrochromic compounds and synthesis and use thereof | SWITCH MATERIALS INC. (CA) | 2013-09-17 | — | — | US | disclosed |
| US-20100190868-A1 | PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS AND SYNTHESIS AND USE THEREOF | SWITCH MATERIALS INC. (CA) | 2010-07-29 | — | — | US | disclosed |
| US-20100190868-A1 | PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS AND SYNTHESIS AND USE THEREOF | SWITCH MATERIALS INC. (CA) | 2010-07-29 | — | — | US | disclosed |
| US-20100190868-A1 | PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS AND SYNTHESIS AND USE THEREOF | SWITCH MATERIALS INC. (CA) | 2010-07-29 | — | — | US | disclosed |
| EP-1888553-A1 | PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS AND SYNTHESIS AND USE THEREOF | Switch Materials Inc. (CA) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125317-A1 | PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS AND SYNTHESIS AND USE THEREOF | SWITCH MATERIALS INC. (CA) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190868-A1 | PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS AND SYNTHESIS AND USE THEREOF | HCN2, HCN1, SCO2 | ALDH1A1 488/4885LMNA 1079/4885MAPK1 2739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.