SCHEMBL248005

SCHEMBL248005

CC(=O)c1cc(C)sc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 4/20 0.42
LMNA P02545 1/20 0.42
MAPK1 P28482 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
MAPT P10636 3/20 0.39
GAA P10253 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PLA2G10 O15496 1/20 0.39
GSK3B P49841 1/20 0.38
ALOX5 P09917 1/20 0.38
TSHR P16473 1/20 0.37
KDM4E B2RXH2 2/20 0.36
KDR P35968 2/20 0.36
PSMD14 O00487 1/20 0.36
MMP2 P08253 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2996683 0.83 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1LMNAMAPK1NPC1
SCHEMBL11848005 0.83 ALDH1A1 (0.44) ALDH1A1LMNAMAPK1NPC1RAB9A
SCHEMBL287087 0.81 ALDH1A1 (0.57) SMN1; SMN2ALDH1A1LMNAMAPK1NPC1
SCHEMBL13889735 0.80 ALDH1A1 (0.36) ALDH1A1LMNAMAPK1NPC1RAB9A
SCHEMBL17367390 0.79 PLA2G10 (0.49) ALDH1A1LMNAMAPK1NPC1RAB9A
SCHEMBL11449568 0.79 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1LMNAMAPK1MAPT
SCHEMBL11845297 0.79 ALDH1A1 (0.41) ALDH1A1LMNAMAPK1NPC1RAB9A
SCHEMBL11338456 0.79 GSK3B (0.50) SMN1; SMN2ALDH1A1LMNAMAPK1NPC1
SCHEMBL23151886 0.77 MAPT (0.47) SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A
SCHEMBL11728556 0.77 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1LMNAMAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4129065-B1 MAMMAL REPELLENT SCENT SCIENCE INT INC (JP) 2025-06-11 EP claimed
CN-119972363-A Flotation collector for phosphorite with high harmful impurities and application thereof 中蓝连海设计研究院有限公司 2025-05-13 CN claimed
CN-119350292-A Preparation method of 3-acetyl-2, 5-dimethylthiophene 石河子大学 2025-01-24 CN claimed
US-20230363389-A1 MAMMAL REPELLENT SCENT SCIENCE INTERNATIONAL INC. (JP) 2023-11-16 US claimed
EP-4129065-A1 MAMMAL REPELLENT Scent Science International Inc. (JP) 2023-02-08 EP claimed
CN-110082441-B Method and kit for detecting forbidden essences 中国检验检疫科学研究院 2022-03-01 CN claimed
CN-113244261-A Application of CAP activated physiological saline in cell metabolism regulation and tumor treatment and medicine 西安交通大学 2021-08-13 CN claimed
US-10920176-B2 Transparent liquids, in particular fabric treatment agents, comprising perfume and microcapsules with an odor modulator compound HENKEL AG & CO. KGAA (DE) 2021-02-16 US claimed
CN-107144656-B Method for measuring 3-acetyl-2, 5-dimethyl thiophene in edible essence by GC-MS/MS (gas chromatography-Mass Spectrometry/Mass Spectrometry) 浙江省食品药品检验研究院 2020-03-31 CN claimed
CN-107064358-B Method for detecting 3-acetyl-2,5-dimethylthiophene by combining magnetic solid-phase extraction with high performance liquid chromatography 广西中烟工业有限责任公司 2020-01-17 CN claimed
US-20180201883-A1 TRANSPARENT LIQUIDS, IN PARTICULAR FABRIC TREATMENT AGENTS, COMPRISING PERFUME AND MICROCAPSULES WITH AN ODOR MODULATOR COMPOUND HENKEL AG & CO. KGAA (DE) 2018-07-19 US claimed
WO-2017046055-A1 PERFUME COMPOSITIONS COMPRISING MICROCAPSULES, FRAGRANCE MODULATOR COMPOUNDS AND FRAGRANCE RAW MATERIAL FOR INCREASING AND PROLONGING THE INTENSITY OF FRAGRANCE HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
WO-2017046052-A1 PERFUME COMPOSITION COMPRISING FRAGRANCE MODULATOR COMPOUNDS AND SILICIC ACID ESTERS FOR INCREASING AND PROLONGING THE INTENSITY OF FRAGRANCE HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
WO-2017046050-A1 LIQUID CLEANING AGENT HAVING OPTIMIZED SCENT HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
WO-2017046054-A1 PERFUME COMPOSITION COMPRISING AN ODOR MODULATOR COMPOUND, AMINO ALCOHOL AND ODORIFEROUS ALDEHYDE AND/OR ODORIFEROUS KETONE FOR INCREASING AND PROLONGING ODOR INTENSITY HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
WO-2017046051-A1 PERFUME COMPOSITION COMPRISING FRAGRANCE MODULATOR COMPOUNDS AND 1-AZA-3,7-DIOXABICYCLO[3.3.0]OCTANE COMPOUNDS FOR INCREASING AND PROLONGING THE INTENSITY OF FRAGRANCE HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
WO-2017046282-A1 TRANSPARENT LIQUIDS, IN PARTICULAR FABRIC TREATMENT AGENTS, CONTAINING PERFUME AND MICROCAPSULES WITH AN ODOR MODULATOR COMPOUND HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
WO-2009131692-A1 SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2009-10-29 WO claimed
US-5665504-A Simulated photographic-quality prints using a plasticizer to reduce curl XEROX CORPORATION (US) 1997-09-09 US claimed
US-4293579-A Flavoring with 3,5-di-(2-methylpropyl)-1,2,4-trithiolane INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-10-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10920176-B2 Transparent liquids, in particular fabric treatment agents, comprising perfume and microcapsules with an odor modulator compound NEFM, TRPA1, ALOX5 SMN1; SMN2 2955/4885ALDH1A1 2979/4885LMNA 3414/4885
US-20230363389-A1 MAMMAL REPELLENT TMT1A, L3MBTL1, NAAA SMN1; SMN2 3029/4885ALDH1A1 702/4885LMNA 3956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.