Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26690441 | 1.00 | HTR1A (1.00) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL26612713 | 0.98 | HTR1A (0.97) | HTR1AHTR7 | |
| SCHEMBL16687760 | 0.86 | HTR1A (0.75) | HTR1AHTR7 | |
| SCHEMBL9945843 | 0.85 | HTR1A (1.00) | HTR1AHTR7 | |
| SCHEMBL3311285 | 0.84 | HTR1A (0.71) | HTR1AHTR7 | |
| SCHEMBL9945840 | 0.83 | HTR1A (1.00) | HTR1AHTR7 | |
| SCHEMBL9945842 | 0.83 | HTR1A (1.00) | HTR1AHTR7 | |
| SCHEMBL23425387 | 0.82 | HTR1A (1.00) | HTR1AHTR7 | |
| SCHEMBL17274574 | 0.82 | HTR1A (1.00) | HTR1AHTR7 | |
| SCHEMBL30831827 | 0.82 | HTR1A (1.00) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200287-A2 | SEROTONIN RECEPTOR MODULATORS | Northeastern University (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040395-A2 | SEROTONIN RECEPTOR MODULATORS | NORTHEASTERN UNIVERSITY (US) | 2022-02-24 | — | — | WO | disclosed |
| US-11021435-B2 | Serotonin receptor-targeting compounds and methods | NORTHEASTERN UNIVERSITY (US) | 2021-06-01 | — | — | US | disclosed |
| US-10017458-B2 | Therapeutic tetrahydronaphthalene compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-07-10 | — | — | US | disclosed |
| US-10017458-B2 | Therapeutic tetrahydronaphthalene compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-07-10 | — | — | US | disclosed |
| US-10017458-B2 | Therapeutic tetrahydronaphthalene compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-07-10 | — | — | US | disclosed |
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-23 | — | — | US | disclosed |
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-23 | — | — | US | disclosed |
| US-9422229-B2 | Therapeutic compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150315127-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2015-11-05 | — | — | US | disclosed |
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| EP-2427183-A2 | THERAPEUTIC COMPOUNDS | University of Florida Research Foundation, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20100305212-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| WO-2010129048-A2 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010129048-A2 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| EP-2164324-A1 | THERAPEUTIC COMPOUNDS | University Of Florida Research Foundation (US) | 2010-03-24 | — | — | EP | disclosed |
| WO-2009061436-A1 | COMPOUND FOR ACTIVATING 5-HT2C RECEPTORS IN COMBINATION WITH AN AMPHETAMINE COMPOUND | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2009-05-14 | — | — | WO | disclosed |
| WO-2008156707-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | HTR1A 13/4885HTR7 22/4885 |
| US-10017458-B2 | Therapeutic tetrahydronaphthalene compounds | HTR2C, HTR2A, HTR3C | HTR1A 9/4885HTR7 22/4885 |
| US-20150315127-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | HTR1A 13/4885HTR7 22/4885 |
| US-11021435-B2 | Serotonin receptor-targeting compounds and methods | HTR1A, HTR2C, HTR7 | HTR1A 1/4885HTR7 3/4885 |
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | HTR1A, HTR2C, HTR7 | HTR1A 1/4885HTR7 3/4885 |
| US-20100305212-A1 | THERAPEUTIC COMPOUNDS | HTR2C, HTR3B, HTR2A | HTR1A 12/4885HTR7 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.