Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.62 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.62 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29023902 | 1.00 | POLB (1.00) | POLBPKMALDH1A1KDM4ELMNA | |
| SCHEMBL30209700 | 0.91 | POLB (0.83) | POLBPKMALDH1A1KDM4ELMNA | |
| SCHEMBL1471970 | 0.87 | POLB (0.76) | POLBPKMALDH1A1KDM4ELMNA | |
| SCHEMBL9210342 | 0.84 | POLB (0.72) | POLBPKMALDH1A1KDM4ELMNA | |
| SCHEMBL7770299 | 0.82 | MEN1 (0.71) | POLBPKMALDH1A1KDM4ELMNA | |
| SCHEMBL15952993 | 0.82 | ALDH1A1 (0.69) | POLBPKMALDH1A1KDM4ELMNA | |
| SCHEMBL16863131 | 0.80 | POLB (0.67) | POLBPKMALDH1A1KDM4ELMNA | |
| SCHEMBL30354961 | 0.80 | POLB (0.67) | POLBPKMALDH1A1KDM4ELMNA | |
| SCHEMBL29023883 | 0.80 | MEN1 (0.69) | POLBPKMALDH1A1KDM4ELMNA | |
| SCHEMBL16177989 | 0.80 | ALDH1A1 (0.72) | POLBPKMALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124459-A | Method for selectively nitrating N- (2-pyridyl) benzene sulfonamide compound | 宁波大学 | 2022-09-30 | — | — | CN | disclosed |