Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | CDKL3 | Q8IVW4 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29969053 | 0.91 | PIM1 (0.41) | PRMT6GRM4CSF1RCYP3A4BACE1 | |
| SCHEMBL29968061 | 0.87 | MAPK8 (0.35) | MAPK8GRM4HTR1ACSF1RAAK1 | |
| SCHEMBL29968294 | 0.86 | ROCK2 (0.38) | MAPK8GRM4HTR1AAAK1MAPK10 | |
| SCHEMBL29967591 | 0.86 | MAPK8 (0.41) | MAPK8CSF1RMAPK10MAPK9PRKD3 | |
| SCHEMBL29968291 | 0.85 | MAPK8 (0.35) | MAPK8GRM4HTR1ACSF1RAAK1 | |
| SCHEMBL29967968 | 0.83 | MAPK10 (0.44) | MAPK8CSF1RAAK1MAPK10MAPK9 | |
| SCHEMBL29969002 | 0.80 | MAPK8 (0.34) | MAPK8GRM4HTR1ACSF1RMAPK10 | |
| SCHEMBL29969011 | 0.80 | MAPK10 (0.36) | MAPK8GRM4CSF1RMAPK10MAPK9 | |
| SCHEMBL29967878 | 0.80 | MAPK10 (0.45) | MAPK8CSF1RAAK1MAPK10MAPK9 | |
| SCHEMBL29967707 | 0.79 | MAPK10 (0.43) | MAPK8CSF1RMAPK10MAPK9FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |