Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967877 | 1.00 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL7547014 | 0.86 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL7547004 | 0.86 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL7547009 | 0.86 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL29968069 | 0.79 | KMT2A (0.57) | L3MBTL1GRM4NPC1RAB9APKM | |
| SCHEMBL29968072 | 0.79 | KMT2A (0.57) | L3MBTL1GRM4NPC1RAB9APKM | |
| SCHEMBL28868985 | 0.79 | KMT2A (0.57) | L3MBTL1GRM4NPC1RAB9APKM | |
| SCHEMBL10773877 | 0.79 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL10773871 | 0.79 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL24704170 | 0.78 | RAB9A (0.49) | PDE4APDE4BPDE4CPDE4DL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206417-B | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115124520-A | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2022-09-30 | — | — | CN | disclosed |