Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547004 | 1.00 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL7547014 | 1.00 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL29967877 | 0.86 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL29967930 | 0.86 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL4821491 | 0.83 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL4821488 | 0.83 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL4823570 | 0.83 | PDE4A (0.90) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL24704170 | 0.81 | RAB9A (0.49) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL10620307 | 0.81 | RAB9A (0.49) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL10620312 | 0.81 | RAB9A (0.49) | PDE4APDE4BPDE4CPDE4DRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020132812-A1 | Oral hypoglycaemic agents | NOVO NORDISK A/S (DK) | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020132812-A1 | Oral hypoglycaemic agents | SLC5A2, GPR119, SLC5A1 | PDE4A 1850/4885PDE4B 1941/4885PDE4C 2747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.