Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 9/20 | 0.41 |
| ▸ | BCR | P11274 | 9/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | WNT1 | P04628 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967815 | 0.92 | SMN1; SMN2 (0.40) | NR1H4ABL1BCRFLT3KIT | |
| SCHEMBL29967707 | 0.86 | MAPK10 (0.43) | ABL1BCRFLT3KITDYRK1A | |
| SCHEMBL29967890 | 0.83 | ACMSD (0.42) | ABL1BCRFLT3KITDYRK1A | |
| SCHEMBL29967802 | 0.79 | FLT3 (0.43) | ABL1BCRFLT3KITDYRK1A | |
| SCHEMBL29967968 | 0.78 | MAPK10 (0.44) | FLT3KITDYRK1ACDC7PLK4 | |
| SCHEMBL31029238 | 0.78 | KDR (0.41) | ABL1BCRFLT3KITDYRK1A | |
| SCHEMBL29968386 | 0.78 | KDM4E (0.44) | ABL1BCRFLT3KITDYRK1A | |
| SCHEMBL29967591 | 0.76 | MAPK8 (0.41) | ABL1FLT3KITDYRK1ACDC7 | |
| SCHEMBL29967878 | 0.75 | MAPK10 (0.45) | FLT3KITDYRK1ACDC7PLK4 | |
| Methyl Benzoate SCHEMBL31029245 | 0.74 | FLT3 (0.43) | ABL1BCRFLT3KITDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |