Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29968184 | 0.98 | PPARG (0.43) | NR1H4RHEBPPARGP2RX3DRD2 | |
| SCHEMBL29968012 | 0.92 | NR1H4 (0.46) | NR1H4PPARGP2RX3DCTPP1 | |
| SCHEMBL29967886 | 0.90 | PPARG (0.40) | PPARGP2RX3DRD2TBXA2R | |
| SCHEMBL29967830 | 0.90 | PLA2G10 (0.42) | PPARGP2RX3 | |
| SCHEMBL29968278 | 0.89 | PPARG (0.49) | NR1H4PPARG | |
| SCHEMBL29968376 | 0.89 | PPARG (0.41) | PPARGP2RX3HRH3 | |
| SCHEMBL29967574 | 0.88 | PPARG (0.41) | PPARGP2RX3 | |
| SCHEMBL29967925 | 0.88 | PPARG (0.49) | NR1H4PPARG | |
| SCHEMBL29967498 | 0.87 | NR1H4 (0.44) | NR1H4PPARGP2RX3 | |
| SCHEMBL29967991 | 0.86 | PPARG (0.58) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |