Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967991 | 0.93 | PPARG (0.58) | PPARGAGTR1AGTR2 | |
| SCHEMBL29968278 | 0.92 | PPARG (0.49) | PPARGAGTR1AGTR2NR1H4 | |
| SCHEMBL29967901 | 0.91 | AGTR1 (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL29967894 | 0.89 | PPARG (0.46) | PPARGAGTR1AGTR2 | |
| SCHEMBL29968012 | 0.88 | NR1H4 (0.46) | PPARGAGTR1AGTR2NR1H4 | |
| SCHEMBL29968167 | 0.88 | NR1H4 (0.44) | PPARGNR1H4 | |
| SCHEMBL29968184 | 0.86 | PPARG (0.43) | PPARGNR1H4 | |
| SCHEMBL29967498 | 0.84 | NR1H4 (0.44) | PPARGNR1H4 | |
| SCHEMBL29968086 | 0.84 | PPARG (0.45) | PPARGAGTR1AGTR2 | |
| SCHEMBL29968169 | 0.84 | NR1H4 (0.37) | PPARGNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |