Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871282 | 1.00 | RORC (0.39) | RORCUSP30GPR119HDAC1TSHR | |
| SCHEMBL20341701 | 0.84 | RORC (0.40) | RORCGPR119HDAC1POLBNR1H2 | |
| SCHEMBL29490365 | 0.83 | ESR2 (0.46) | RORCUSP30GPR119TSHRALOX15 | |
| SCHEMBL20560829 | 0.83 | ESR2 (0.46) | RORCUSP30GPR119TSHRALOX15 | |
| SCHEMBL9901785 | 0.82 | GPR119 (0.44) | RORCUSP30GPR119TACR1PDK2 | |
| SCHEMBL31125398 | 0.82 | STS (0.47) | RORCUSP30GPR119POLBESR2 | |
| SCHEMBL21826203 | 0.82 | STS (0.47) | RORCUSP30GPR119POLBESR2 | |
| SCHEMBL15212259 | 0.82 | RORC (0.48) | RORCUSP30GPR119TSHRALOX15 | |
| SCHEMBL1309072 | 0.81 | RORC (0.51) | RORCGPR119TSHRALOX15ATM | |
| SCHEMBL31084094 | 0.81 | ALDH1A1 (0.52) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |