SCHEMBL29968698

SCHEMBL29968698

COc1cnc(-c2ccccn2)nc1NC(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 11/20 1.00
L3MBTL1 Q9Y468 8/20 1.00
SMN1; SMN2 Q16637 7/20 1.00
LMNA P02545 5/20 1.00
MAPT P10636 3/20 1.00
MITF O75030 1/20 1.00
KDM4E B2RXH2 2/20 0.58
HTT P42858 2/20 0.58
ALDH1A1 P00352 4/20 0.54
MEN1 O00255 3/20 0.54
PPP1CA P62136 3/20 0.54
KMT2A Q03164 3/20 0.54
TDP1 Q9NUW8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1701097 1.00 TRPM8 (1.00) TRPM8L3MBTL1SMN1; SMN2LMNAMAPT
Fumaric Acid SCHEMBL1701484 0.91 TRPM8 (0.82) TRPM8L3MBTL1SMN1; SMN2LMNAMAPT
Fumaric Acid SCHEMBL13277766 0.91 TRPM8 (0.82) TRPM8L3MBTL1SMN1; SMN2LMNAMAPT
Fumaric Acid SCHEMBL13277769 0.91 TRPM8 (0.82) TRPM8L3MBTL1SMN1; SMN2LMNAMAPT
Fumaric Acid SCHEMBL13277768 0.91 TRPM8 (0.82) TRPM8L3MBTL1SMN1; SMN2LMNAMAPT
Succinic Acid SCHEMBL13277748 0.90 TRPM8 (0.80) TRPM8L3MBTL1SMN1; SMN2LMNAMAPT
Succinic Acid SCHEMBL1701275 0.90 TRPM8 (0.80) TRPM8L3MBTL1SMN1; SMN2LMNAMAPT
Cadaverine Tartrate SCHEMBL1701294 0.90 TRPM8 (0.80) TRPM8L3MBTL1SMN1; SMN2LMNAMAPT
Cadaverine Tartrate SCHEMBL13277601 0.90 TRPM8 (0.80) TRPM8L3MBTL1SMN1; SMN2LMNAMAPT
SCHEMBL1699152 0.90 TRPM8 (1.00) TRPM8L3MBTL1SMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119604269-A Composition for enhancing cooling effect 弗门尼舍公司 2025-03-11 CN disclosed
EP-3663366-B1 USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS SYMRISE AG (DE) 2025-01-08 EP disclosed
CN-118414086-A Antimicrobial compositions with encapsulated colorants 弗门尼舍有限公司 2024-07-30 CN disclosed
CN-117715614-A Quick-drying perfume composition 弗门尼舍有限公司 2024-03-15 CN disclosed
CN-117693332-A Oral care compositions 弗门尼舍有限公司 2024-03-12 CN disclosed
CN-117479843-A Composition for enhancing cooling effect 弗门尼舍公司 2024-01-30 CN disclosed
CN-116744889-A Composition for enhancing cooling effect 弗门尼舍公司 2023-09-12 CN disclosed
CN-111053775-B Physiologically cool active ingredient and use of substances containing such active ingredient 西姆莱斯股份公司 2023-08-18 CN disclosed
EP-4171266-A1 SWEETENING COMPOSITIONS AND USES THEREOF Firmenich SA (CH) 2023-05-03 EP disclosed
CN-115988967-A Composition for reducing peroxide odor and application thereof 弗门尼舍有限公司 2023-04-18 CN disclosed
CN-115701912-A Sweetening compositions and uses thereof 弗门尼舍有限公司 2023-02-14 CN disclosed
CN-115697082-A Wintergreen flavor composition without methyl salicylate 弗门尼舍有限公司 2023-02-03 CN disclosed
CN-115551598-A Reduction of undesirable taste profile in oral care products 弗门尼舍有限公司 2022-12-30 CN disclosed
CN-115279414-A Composition for reducing salty taste and use thereof 弗门尼舍有限公司 2022-11-01 CN disclosed