SCHEMBL29969239

SCHEMBL29969239

CC(C)(c1ccc(OS(=O)(=O)Oc2ccc3ccc(=O)oc3c2)cc1)c1ccc(OS(=O)(=O)Oc2ccc3ccc(=O)oc3c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 2/20 0.61
GAA P10253 2/20 0.61
STS P08842 1/20 0.61
MAOB P27338 2/20 0.56
CA12 O43570 12/20 0.55
CA9 Q16790 11/20 0.55
CA1 P00915 11/20 0.55
CA7 P43166 5/20 0.55
CA4 P22748 5/20 0.55
CA6 P23280 4/20 0.55
CA14 Q9ULX7 4/20 0.55
CA5A P35218 4/20 0.55
KDM4E B2RXH2 3/20 0.55
CA3 P07451 2/20 0.55
ALDH1A1 P00352 2/20 0.55
AKR1B1 P15121 1/20 0.55
HPGD P15428 1/20 0.55
HSD17B10 Q99714 1/20 0.55
SRD5A1 P18405 1/20 0.52
CA5B Q9Y2D0 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4419653 0.82 GLA (0.68) GLAGAASTSMAOBCA12
7-Methanesulfonyloxycoumarin SCHEMBL10851014 0.79 GAA (0.71) GLAGAASTSMAOBCA12
SCHEMBL9432106 0.77 GLA (0.68) GLAGAASTSMAOBCA12
Hydrogen Sulfide SCHEMBL6875323 0.76 MAOB (0.68) GLAGAASTSMAOBCA12
SCHEMBL17318081 0.76 GLA (0.71) GLAGAASTSMAOBCA12
SCHEMBL561434 0.76 GLA (1.00) GLAGAASTSMAOBCA12
Hydrogen Sulfide SCHEMBL6878856 0.75 GLA (0.66) GLAGAASTSMAOBCA12
SCHEMBL10848120 0.75 GLA (0.66) GLAGAASTSMAOBCA12
Potassium Ion SCHEMBL29669597 0.75 GLA (0.69) GLAGAASTSMAOBCA12
SCHEMBL16283610 0.74 SRD5A1 (0.70) GLAGAASTSCA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2025-08-19 US disclosed
EP-4295841-A2 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION The Scripps Research Institute (US) 2023-12-27 EP disclosed
EP-3892610-B1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION SCRIPPS RESEARCH INST (US) 2023-08-16 EP disclosed
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof GRB2, SCTR, OGFR GLA 3805/4885GAA 3905/4885STS 278/4885
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF QSOX1, YBX1, SFXN1 GLA 1309/4885GAA 2319/4885STS 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.