Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 9/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20990490 | 0.75 | AHR (1.00) | AHRMDM2JAK2ALDH1A1HPGD | |
| SCHEMBL5044997 | 0.73 | AHR (0.49) | AHRMDM2JAK2TOP2ACDK5 | |
| SCHEMBL20990484 | 0.72 | AHR (0.70) | AHRMDM2JAK2CDK2 | |
| SCHEMBL9386045 | 0.71 | AHR (0.47) | AHRMDM2JAK2TOP2AGSK3B | |
| SCHEMBL20990487 | 0.70 | AHR (0.73) | AHRMDM2JAK2GSK3BCDK5 | |
| SCHEMBL20990482 | 0.70 | AHR (0.73) | AHRMDM2JAK2GSK3BCDK5 | |
| SCHEMBL25777055 | 0.70 | TOP2A (0.48) | AHRMDM2JAK2CASP1HSD17B10 | |
| SCHEMBL421641 | 0.68 | AHR (0.54) | AHRMDM2JAK2GSK3BCDK5 | |
| SCHEMBL31603697 | 0.68 | MAOA (0.42) | AHRMAOAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL21886344 | 0.67 | ALDH1A1 (0.64) | AHRMAOAL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11466021-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11466021-B2 | Materials for organic electroluminescent devices | OR10J3, L1CAM, EPCAM | AHR 3241/4885MAOA 343/4885MDM2 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.