Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 13/20 | 0.49 |
| ▸ | THRA | P10827 | 11/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 2/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4215849 | 1.00 | THRB (0.49) | THRBTHRARORCCETPGCGR | |
| SCHEMBL25950026 | 0.93 | THRB (0.43) | THRBTHRARORC | |
| SCHEMBL282009 | 0.89 | THRB (0.44) | THRBTHRACETPCALM1 | |
| SCHEMBL25338282 | 0.89 | THRB (0.49) | THRBTHRARORCCETPCSNK2A1 | |
| SCHEMBL25949873 | 0.88 | THRB (0.44) | THRBTHRARORCCSNK2A1 | |
| SCHEMBL31041193 | 0.86 | THRB (0.48) | THRBTHRA | |
| SCHEMBL282106 | 0.86 | THRB (0.48) | THRBTHRA | |
| SCHEMBL282105 | 0.86 | THRB (0.51) | THRBTHRARORCCETPALOX15 | |
| SCHEMBL23462597 | 0.85 | THRB (0.45) | THRBTHRARORCCETPALOX15 | |
| SCHEMBL30286018 | 0.84 | THRB (0.44) | THRBTHRARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279359-A | Novel thyromimetic agents | 速通医疗公司 | 2022-11-01 | — | — | CN | disclosed |