Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.44 |
| ▸ | THRA | P10827 | 6/20 | 0.44 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196600 | 0.87 | THRB (0.43) | THRBTHRATACR2FDPS | |
| SCHEMBL30286039 | 0.85 | THRB (0.47) | THRBTHRAALDH1A1RORCTDP1 | |
| SCHEMBL25949873 | 0.84 | THRB (0.44) | THRBTHRAALDH1A1MEN1KMT2A | |
| SCHEMBL4215849 | 0.84 | THRB (0.49) | THRBTHRARORC | |
| SCHEMBL29970905 | 0.84 | THRB (0.49) | THRBTHRARORC | |
| SCHEMBL24132943 | 0.84 | THRA (0.45) | THRBTHRATACR2ALDH1A1MAPT | |
| SCHEMBL25338282 | 0.83 | THRB (0.49) | THRBTHRAMAPTRORCHPGD | |
| SCHEMBL25950441 | 0.83 | THRB (0.38) | THRBTHRATACR2 | |
| SCHEMBL25949875 | 0.80 | THRB (0.44) | THRBTHRAMEN1KMT2AL3MBTL1 | |
| SCHEMBL3165436 | 0.79 | THRB (0.59) | THRBTHRARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916740-A | Thyromimetic agents | 速通医疗公司 | 2023-04-04 | — | — | CN | disclosed |