SCHEMBL25949873

SCHEMBL25949873

COCOc1ccc(Cc2c(Cl)cc(CCl)cc2Cl)cc1C(C)C

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 9/20 0.44
THRA P10827 7/20 0.44
RORC P51449 1/20 0.39
CSNK2A1 P68400 3/20 0.33
TTR P02766 1/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
CA2 P00918 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25950052 0.93 THRB (0.39) THRBTHRARORCCSNK2A1TTR
SCHEMBL25338282 0.91 THRB (0.49) THRBTHRARORCCSNK2A1TTR
SCHEMBL4215849 0.88 THRB (0.49) THRBTHRARORCCSNK2A1
SCHEMBL29970905 0.88 THRB (0.49) THRBTHRARORCCSNK2A1
SCHEMBL25950055 0.85 THRB (0.46) THRBTHRARORC
SCHEMBL30286018 0.84 THRB (0.44) THRBTHRARORCMEN1ALDH1A1
SCHEMBL25949868 0.81 THRB (0.38) THRBTHRARORC
SCHEMBL25950026 0.81 THRB (0.43) THRBTHRARORC
SCHEMBL25950141 0.81 THRB (0.43) THRBTHRARORCTTR
SCHEMBL30483268 0.81 THRB (0.44) THRBTHRARORCMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242471-A1 THYROMIMETICS AUTOBAHN THERAPEUTICS, INC. 2023-08-03 US disclosed
EP-4168384-A1 THYROMIMETICS Autobahn Therapeutics, Inc. (US) 2023-04-26 EP disclosed
CN-115916740-A Thyromimetic agents 速通医疗公司 2023-04-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242471-A1 THYROMIMETICS TPO, THOP1, THRB THRB 3/4885THRA 6/4885RORC 630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.