Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.43 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.41 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12527286 | 0.90 | MMP13 (0.43) | NAMPTMMP13MMP1GAA | |
| SCHEMBL25307668 | 0.90 | MMP13 (0.43) | NAMPTMMP13MMP1GAA | |
| SCHEMBL21808030 | 0.90 | MMP13 (0.43) | NAMPTMMP13MMP1GAA | |
| SCHEMBL12705613 | 0.83 | GAA (0.46) | ALDH1A1TSHRACHECYP3A4MMP13 | |
| SCHEMBL14227971 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRACHECYP3A4MMP13 | |
| SCHEMBL879307 | 0.81 | ACHE (0.53) | ALDH1A1TSHRACHECYP3A4MMP13 | |
| SCHEMBL5319901 | 0.80 | MMP13 (0.45) | ALDH1A1TSHRACHECYP3A4MMP13 | |
| SCHEMBL11507747 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRACHECYP3A4MMP13 | |
| SCHEMBL5761130 | 0.77 | GAA (0.52) | ALDH1A1TSHRACHECYP3A4MMP13 | |
| SCHEMBL2114286 | 0.75 | CRBN (0.45) | SLC12A2SLC12A5ALDH1A1TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279747-A | Novel fYN and VEGFR2 kinase inhibitors | 罗达制药生物技术有限责任公司 | 2022-11-01 | — | — | CN | disclosed |