SCHEMBL28654286

SCHEMBL28654286

O=C(O)c1cc(S(=O)(=O)F)ccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.53
FTO Q9C0B1 5/20 0.53
ALKBH5 Q6P6C2 4/20 0.53
ALDH1A1 P00352 3/20 0.53
ASPH Q12797 2/20 0.53
KDM8 Q8N371 2/20 0.53
KDM5A P29375 2/20 0.53
KDM3A Q9Y4C1 2/20 0.53
KDM4A O75164 2/20 0.53
KDM5C P41229 2/20 0.53
KDM5B Q9UGL1 2/20 0.53
KDM6B O15054 1/20 0.53
TET3 O43151 1/20 0.53
BBOX1 O75936 1/20 0.53
MAPT P10636 1/20 0.53
KDM4D Q6B0I6 1/20 0.53
TET2 Q6N021 1/20 0.53
KDM7A Q6ZMT4 1/20 0.53
TET1 Q8NFU7 1/20 0.53
EGLN2 Q96KS0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930744 0.83 KDM4E (0.55) KDM4EFTOALKBH5ALDH1A1ASPH
SCHEMBL30525023 0.81 KDM4E (0.53) KDM4EFTOALKBH5ALDH1A1ASPH
SCHEMBL20790368 0.81 KDM4E (0.53) KDM4EFTOALKBH5ALDH1A1ASPH
SCHEMBL22221305 0.81 ALDH1A1 (0.56) KDM4EFTOALKBH5ALDH1A1ASPH
SCHEMBL23497385 0.76 KDM4E (0.47) KDM4EFTOALKBH5ALDH1A1ASPH
SCHEMBL29971106 0.76 KDM4E (0.47) KDM4EFTOALKBH5ALDH1A1ASPH
SCHEMBL7513922 0.73 KMO (0.71) KDM4EFTOALKBH5ALDH1A1ASPH
SCHEMBL30800092 0.73 KMO (0.71) KDM4EFTOALKBH5ALDH1A1ASPH
SCHEMBL231979 0.72 KDM4E (0.61) KDM4EFTOALKBH5ALDH1A1ASPH
SCHEMBL9585979 0.72 FTO (0.96) KDM4EFTOALKBH5ALDH1A1ASPH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527536-B Fluorine-containing polysaccharide high molecular compound and preparation method thereof 杭州德柯医疗科技有限公司 2024-03-22 CN claimed
CN-113527536-A Fluorine-containing polysaccharide high molecular compound and preparation method thereof 杭州德柯医疗科技有限公司 2021-10-22 CN claimed
CN-113527536-B Fluorine-containing polysaccharide high molecular compound and preparation method thereof 杭州德柯医疗科技有限公司 2024-03-22 CN disclosed
CN-113527536-A Fluorine-containing polysaccharide high molecular compound and preparation method thereof 杭州德柯医疗科技有限公司 2021-10-22 CN disclosed