Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.55 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.55 |
| ▸ | KDM4A | O75164 | 3/20 | 0.55 |
| ▸ | KDM5C | P41229 | 3/20 | 0.55 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.55 |
| ▸ | KDM6B | O15054 | 2/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.55 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.55 |
| ▸ | KDM5A | P29375 | 2/20 | 0.55 |
| ▸ | TET3 | O43151 | 1/20 | 0.55 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ASPH | Q12797 | 1/20 | 0.55 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.55 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.55 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.55 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654286 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1ALKBH5FTOKDM4A | |
| SCHEMBL20790368 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1ALKBH5FTOKDM4A | |
| SCHEMBL30525023 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1ALKBH5FTOKDM4A | |
| SCHEMBL22221305 | 0.79 | ALDH1A1 (0.56) | KDM4EALDH1A1ALKBH5FTOKDM4A | |
| SCHEMBL23497385 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1ALKBH5FTOKDM4A | |
| SCHEMBL29971106 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1ALKBH5FTOKDM4A | |
| SCHEMBL1072803 | 0.77 | ALDH1A1 (0.43) | KDM4EALDH1A1KDM4AKDM5CKDM3A | |
| SCHEMBL29774730 | 0.77 | ALDH1A1 (0.43) | KDM4EALDH1A1KDM4AKDM5CKDM3A | |
| SCHEMBL30800092 | 0.74 | KMO (0.71) | KDM4EALDH1A1ALKBH5FTOKDM4A | |
| SCHEMBL7513922 | 0.74 | KMO (0.71) | KDM4EALDH1A1ALKBH5FTOKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1250565-C | Synthesis of proteins by native chemical ligation | SCRIPPS RESEARCH INST (US) | 2006-04-12 | — | — | CN | claimed |
| CN-1187823-A | Synthesis of proteins by native chemical ligation | SCRIPPS RESEARCH INST (US) | 1998-07-15 | — | — | CN | claimed |
| CN-1810837-A | Synthesis of proteins by native chemical ligation | SCRIPPS RESEARCH INST (US) | 2006-08-02 | — | — | CN | disclosed |
| CN-1250565-C | Synthesis of proteins by native chemical ligation | SCRIPPS RESEARCH INST (US) | 2006-04-12 | — | — | CN | disclosed |
| CN-1451013-A | Nucleophile-stable thoester generating compounds, method of production and use | GRYPHON SCIENCES (US) | 2003-10-22 | — | — | CN | disclosed |
| EP-1128729-A1 | HERBICIDAL COMPOSITION | Syngenta Participations AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027203-A1 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2000-05-18 | — | — | WO | disclosed |
| CN-1187823-A | Synthesis of proteins by native chemical ligation | SCRIPPS RESEARCH INST (US) | 1998-07-15 | — | — | CN | disclosed |