Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.45 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 4/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | CKS1B | P61024 | 2/20 | 0.38 |
| ▸ | SKP1 | P63208 | 2/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259891 | 0.94 | LOXL2 (0.46) | LOXL2LOXL3PDPK1HDAC1ACACB | |
| SCHEMBL19274636 | 0.90 | LOXL2 (0.45) | LOXL2LOXL3PDPK1HDAC1ACACB | |
| SCHEMBL19274640 | 0.90 | LOXL2 (0.40) | LOXL2LOXL3PDPK1HDAC1ACACB | |
| SCHEMBL30699957 | 0.90 | LOXL2 (0.40) | LOXL2LOXL3PDPK1HDAC1ACACB | |
| SCHEMBL19274309 | 0.89 | LOXL2 (0.45) | LOXL2LOXL3PDPK1HDAC1ACACB | |
| SCHEMBL19274612 | 0.89 | LOXL2 (0.46) | LOXL2LOXL3PDPK1HDAC1ACACB | |
| SCHEMBL28644252 | 0.89 | PDPK1 (0.41) | LOXL2LOXL3PDPK1HDAC1ACACB | |
| SCHEMBL29971072 | 0.89 | PDPK1 (0.41) | LOXL2LOXL3PDPK1HDAC1ACACB | |
| SCHEMBL19274318 | 0.88 | LOXL2 (0.46) | LOXL2LOXL3PDPK1HDAC1ACACB | |
| SCHEMBL19274312 | 0.88 | LOXL3 (0.44) | LOXL2LOXL3PDPK1HDAC1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11608330-B2 | Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2023-03-21 | — | — | US | disclosed |
| US-20220372028-A1 | Methylamine Derivatives as Lysysl Oxidase Inhibitors for the Treatment of Cancer | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2022-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220372028-A1 | Methylamine Derivatives as Lysysl Oxidase Inhibitors for the Treatment of Cancer | LOXL1, LOXL3, LOXL2 | LOXL2 3/4885LOXL3 2/4885PDPK1 4487/4885 |
| US-11608330-B2 | Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer | LOXL1, LOXL3, LOXL2 | LOXL2 3/4885LOXL3 2/4885PDPK1 4487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.