SCHEMBL29971509

SCHEMBL29971509

N=C(N)c1ccccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
ALDH1A1 P00352 3/20 0.50
POLB P06746 2/20 0.46
KDM4E B2RXH2 2/20 0.44
PKM P14618 2/20 0.44
F2 P00734 1/20 0.44
F10 P00742 1/20 0.44
F12 P00748 1/20 0.44
F7 P08709 1/20 0.44
F3 P13726 1/20 0.44
LMNA P02545 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
IDO1 P14902 2/20 0.44
HTT P42858 2/20 0.44
TAAR1 Q96RJ0 2/20 0.44
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
TSHR P16473 1/20 0.43
BLM P54132 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL948047 1.00 CES2 (0.52) CES2CES1ALDH1A1POLBKDM4E
Bromide SCHEMBL9085016 0.98 CES2 (0.50) CES2CES1ALDH1A1POLBKDM4E
Hydrochloric Acid SCHEMBL30013370 0.98 CES2 (0.50) CES2CES1ALDH1A1POLBKDM4E
Hydrochloric Acid SCHEMBL697635 0.98 CES2 (0.50) CES2CES1ALDH1A1POLBKDM4E
SCHEMBL6337922 0.81 TSHR (0.54) CES2CES1ALDH1A1KDM4EPKM
SCHEMBL10495281 0.81 F2 (0.55) ALDH1A1KDM4EPKMF2F10
Hydrochloric Acid SCHEMBL23778651 0.79 TSHR (0.52) ALDH1A1KDM4EPKMF2F10
Hydrochloric Acid SCHEMBL28555632 0.78 BLM (0.57) ALDH1A1KDM4EPKMF2F10
Hydrochloric Acid SCHEMBL29008442 0.78 BLM (0.57) ALDH1A1KDM4EPKMF2F10
SCHEMBL16466032 0.78 ALDH1A1 (0.48) CES2CES1ALDH1A1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4305096-A1 FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS Dupont Specialty Products USA, LLC (US) 2024-01-17 EP disclosed
WO-2022192006-A1 FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS DUPONT POLYMERS, INC. (US) 2022-09-15 WO disclosed