SCHEMBL948047

SCHEMBL948047

N=C(N)c1ccccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
ALDH1A1 P00352 3/20 0.50
POLB P06746 2/20 0.46
KDM4E B2RXH2 2/20 0.44
PKM P14618 2/20 0.44
F2 P00734 1/20 0.44
F10 P00742 1/20 0.44
F12 P00748 1/20 0.44
F7 P08709 1/20 0.44
F3 P13726 1/20 0.44
LMNA P02545 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
IDO1 P14902 2/20 0.44
HTT P42858 2/20 0.44
TAAR1 Q96RJ0 2/20 0.44
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
TSHR P16473 1/20 0.43
BLM P54132 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29971509 1.00 CES2 (0.52) CES2CES1ALDH1A1POLBKDM4E
Bromide SCHEMBL9085016 0.98 CES2 (0.50) CES2CES1ALDH1A1POLBKDM4E
Hydrochloric Acid SCHEMBL30013370 0.98 CES2 (0.50) CES2CES1ALDH1A1POLBKDM4E
Hydrochloric Acid SCHEMBL697635 0.98 CES2 (0.50) CES2CES1ALDH1A1POLBKDM4E
SCHEMBL6337922 0.81 TSHR (0.54) CES2CES1ALDH1A1KDM4EPKM
SCHEMBL10495281 0.81 F2 (0.55) ALDH1A1KDM4EPKMF2F10
Hydrochloric Acid SCHEMBL23778651 0.79 TSHR (0.52) ALDH1A1KDM4EPKMF2F10
Hydrochloric Acid SCHEMBL28555632 0.78 BLM (0.57) ALDH1A1KDM4EPKMF2F10
Hydrochloric Acid SCHEMBL29008442 0.78 BLM (0.57) ALDH1A1KDM4EPKMF2F10
SCHEMBL16466032 0.78 ALDH1A1 (0.48) CES2CES1ALDH1A1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357533-A1 METHOD FOR CHEMICAL UPCYCLING OF RESINS CONTAINING ESTER BONDS ZHEJIANG UNIVERSITY (CN) 2023-11-09 US claimed
WO-2023116710-A1 SPINOSAD HIGH-YIELD STRAIN AND USE THEREOF 山东鲁抗医药股份有限公司 2023-06-29 WO claimed
CN-114752109-A Upgrading recycling method of resin containing ester bonds 浙江大学 2022-07-15 CN claimed
CN-106383189-A Dispersive liquid-liquid microextraction gas chromatograph mass spectrometry pesticide residue detection method 嘉兴职业技术学院 2017-02-08 CN claimed
CN-103598053-A High-yield planting method for desert date trees in saline-alkali soil MA CHUNPING 2014-02-26 CN claimed
EP-0942651-B1 INSECTICIDAL AND MITICIDAL COMPOSITIONS BASF AG (DE) 2003-04-23 EP claimed
US-6337345-B1 CHLORFENAPYR AND FORMAMIDINE INSECTICIDE AMERICAN CYANAMID CO. 2002-01-08 US claimed
CN-1303601-A Coal based acid pesticide SHANXI COAL CHEM INST (CN) 2001-07-18 CN claimed
EP-0103126-B1 PROCESS FOR PREPARING 4-AMINO-5-DIALKOXYMETHYLPYRIMIDINE DERIVATIVES UBE INDUSTRIES, LTD. (JP) 1987-03-04 EP claimed
US-4492792-A Process for preparing 4-amino-5-dialkoxy-methylpyrimidine derivatives UBE INDUSTRIES, LTD. (JP) 1985-01-08 US claimed
EP-0103126-A1 Process for preparing 4-amino-5-dialkoxymethylpyrimidine derivatives UBE INDUSTRIES, LTD. (JP) 1984-03-21 EP claimed
US-12509682-B2 Fatty acid synthase, inhibitors and modifications thereof and its use MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUND DER WISSENSCHAFTEN E.V. (DE) 2025-12-30 US disclosed
US-20250275964-A1 METHODS OF INHIBITING LIVER-TYPE GLUTAMINASE, GLS2 CORNELL UNIVERSITY 2025-09-04 US disclosed
WO-2025099231-A1 FATTY ACID SYNTHASE MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-05-15 WO disclosed
EP-4553163-A1 FATTY ACID SYNTHASE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-05-14 EP disclosed
US-3934020-A Halophenyl acetamidines as anxiolytic antidepressants THE DOW CHEMICAL COMPANY (US) 1976-01-20 US disclosed
US-3934010-A MITICIDE CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3932629-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3932630-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3856947-A INSECTICIDAL COMPOSITIONS AND METHODS OF KILLING INSECTS USING A MIXTURE OF CYTROLANE AND CHLORPHENAMIDINE CTS CHEM & TECH SUPPLIES 1974-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509682-B2 Fatty acid synthase, inhibitors and modifications thereof and its use FASN, FAR1, FADS1 CES2 1753/4885CES1 44/4885ALDH1A1 1136/4885
US-20250275964-A1 METHODS OF INHIBITING LIVER-TYPE GLUTAMINASE, GLS2 GLS2, GLS, GLUL CES2 892/4885CES1 128/4885ALDH1A1 960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.