Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669276 | 1.00 | L3MBTL1 (0.43) | L3MBTL1NTRK1PIM1CASP3KDM4E | |
| SCHEMBL14848254 | 0.82 | CCR1 (0.54) | L3MBTL1NTRK1PIM1CASP3KDM4E | |
| SCHEMBL1656292 | 0.79 | L3MBTL1 (0.43) | L3MBTL1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL2644517 | 0.79 | L3MBTL1 (0.43) | L3MBTL1CASP3KDM4EPKMTP53 | |
| SCHEMBL24921562 | 0.78 | RAB9A (0.56) | L3MBTL1NTRK1PIM1KDM4EPKM | |
| SCHEMBL14946757 | 0.77 | CASP3 (0.42) | L3MBTL1CASP3KDM4EPKMTP53 | |
| SCHEMBL30444561 | 0.76 | L3MBTL1 (0.40) | L3MBTL1CASP3KDM4EPKMMAPT | |
| SCHEMBL13114624 | 0.76 | L3MBTL1 (0.40) | L3MBTL1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL14761932 | 0.76 | L3MBTL1 (0.40) | L3MBTL1CASP3KDM4EPKMMAPT | |
| SCHEMBL15495537 | 0.76 | CASP3 (0.56) | L3MBTL1CASP3KDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845778-A | Dihydrocyclopentaisoquinoline sulfonamide derivative compound | UCB生物制药有限责任公司 | 2022-08-02 | — | — | CN | disclosed |