Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17111481 | 1.00 | KDM4E (0.55) | KDM4ELMNAALDH1A1GLAHPGD | |
| SCHEMBL9902524 | 0.82 | IMPDH2 (0.39) | KDM4ELMNAALDH1A1GLAHPGD | |
| SCHEMBL5217367 | 0.77 | KDM4E (0.47) | KDM4ELMNAALDH1A1GLAHPGD | |
| SCHEMBL27839029 | 0.77 | MAP2K3 (0.55) | KDM4ELMNAALDH1A1GLAHPGD | |
| SCHEMBL31677629 | 0.76 | PIK3CD (0.37) | KDM4ELMNAALDH1A1GLAHPGD | |
| SCHEMBL31677601 | 0.76 | EGLN2 (0.40) | ADORA2AADORA1GAA | |
| SCHEMBL15716741 | 0.75 | ALDH1A1 (0.45) | KDM4ELMNAALDH1A1GLAHPGD | |
| SCHEMBL16712892 | 0.75 | ALDH1A1 (0.45) | KDM4ELMNAALDH1A1GLAHPGD | |
| SCHEMBL15716526 | 0.75 | ADORA2A (0.49) | KDM4ELMNAALDH1A1GLAHPGD | |
| SCHEMBL18136468 | 0.75 | LMNA (0.48) | KDM4ELMNAALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |