⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29973164 | 0.91 | — | — | |
| SCHEMBL29973340 | 0.75 | KEAP1 (0.40) | — | |
| SCHEMBL6692693 | 0.65 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL23579206 | 0.65 | — | — | |
| SCHEMBL17580422 | 0.63 | — | — | |
| SCHEMBL20876924 | 0.62 | — | — | |
| SCHEMBL23609413 | 0.62 | KDM4E (0.40) | — | |
| SCHEMBL29974830 | 0.61 | MAPT (0.37) | — | |
| SCHEMBL30701837 | 0.61 | LMNA (0.35) | — | |
| SCHEMBL22720027 | 0.60 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |