Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091333 | 0.78 | HTR6 (0.53) | HTR6HTR2AALDH1A1KDM4EMEN1 | |
| Benzene SCHEMBL28734247 | 0.76 | HTR6 (0.51) | HTR6HTR2AALDH1A1KDM4EMEN1 | |
| SCHEMBL29386036 | 0.72 | HTR2A (0.39) | HTR6HTR2AKDM4EMEN1KMT2A | |
| SCHEMBL19630560 | 0.72 | HTR2A (0.39) | HTR6HTR2AKDM4EMEN1KMT2A | |
| SCHEMBL27460809 | 0.70 | HTR2A (0.40) | HTR6HTR2AKDM4EMEN1KMT2A | |
| SCHEMBL15661810 | 0.69 | KDM1A (0.38) | HTR6HTR2AMEN1KMT2ASIGMAR1 | |
| SCHEMBL9062195 | 0.69 | HTR2A (0.36) | HTR6HTR2AALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL30769837 | 0.69 | HTR2A (0.36) | HTR6HTR2AKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30769631 | 0.69 | HTR2A (0.36) | HTR6HTR2AKDM4EMEN1KMT2A | |
| SCHEMBL2830663 | 0.69 | HTR2C (0.37) | HTR6HTR2AKDM4ERETCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |