Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.45 |
| ▸ | PTGES | O14684 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 15/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3013327 | 0.93 | PTGES (0.43) | ALOX5APPTGESPPARGPPARA | |
| SCHEMBL2997573 | 0.90 | ALOX5AP (0.44) | ALOX5APPTGESPPARGPPARACYP3A4 | |
| SCHEMBL3011271 | 0.88 | PTGES (0.45) | PTGESPPARGPPARA | |
| SCHEMBL334396 | 0.88 | PTGES (0.45) | PTGESPPARGPPARA | |
| SCHEMBL3001794 | 0.88 | PTGES (0.45) | PTGESPPARGPPARA | |
| SCHEMBL3572273 | 0.87 | PTGES (0.45) | PTGESPPARGPPARA | |
| SCHEMBL334351 | 0.87 | PTGES (0.45) | ALOX5APPTGESPPARGPPARA | |
| SCHEMBL3006446 | 0.87 | PTGES (0.44) | PTGESPPARGPPARA | |
| SCHEMBL3013088 | 0.86 | PTGES (0.45) | PTGESPPARGPPARA | |
| SCHEMBL3009821 | 0.85 | PTGES (0.43) | PTGESPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, TPH1 | ALOX5AP 1106/4885PTGES 33/4885PPARG 2505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.