Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.44 |
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3010510 | 0.93 | PTGES (0.38) | ALOX5APPTGESPPARGPPARAKDM4E | |
| Hydrochloric Acid SCHEMBL3010507 | 0.92 | PTGES (0.38) | ALOX5APPTGESPPARGPPARAKDM4E | |
| SCHEMBL3001790 | 0.90 | KDM4E (0.40) | ALOX5APPTGESPPARGPPARAKDM4E | |
| SCHEMBL2997313 | 0.90 | ALOX5AP (0.45) | ALOX5APPTGESPPARGPPARACYP3A4 | |
| SCHEMBL2997500 | 0.89 | KDM4E (0.40) | ALOX5APPTGESPPARGPPARAKDM4E | |
| SCHEMBL3008051 | 0.88 | KDM4E (0.39) | ALOX5APPTGESPPARGPPARAKDM4E | |
| SCHEMBL3006452 | 0.88 | KDM4E (0.39) | ALOX5APPTGESPPARGPPARAKDM4E | |
| SCHEMBL3001004 | 0.88 | KDM4E (0.39) | ALOX5APPTGESPPARGPPARAKDM4E | |
| SCHEMBL3000835 | 0.88 | KMT2A (0.43) | PTGESPPARGPPARAKDM4EL3MBTL1 | |
| SCHEMBL334166 | 0.87 | PTGES (0.40) | ALOX5APPTGESPPARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, TPH1 | ALOX5AP 1106/4885PTGES 33/4885PPARG 2505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.