Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579269 | 1.00 | PDK1 (0.39) | PDK1PDK2PDK3PDK4ACHE | |
| SCHEMBL23609281 | 0.83 | AR (0.38) | PDK1PDK2PDK3PDK4CHRM2 | |
| SCHEMBL23579395 | 0.81 | NPC1 (0.35) | PDK1PDK2PDK3PDK4AAK1 | |
| SCHEMBL6501239 | 0.79 | PDK1 (0.41) | PDK1PDK2PDK3PDK4CHRM2 | |
| SCHEMBL6493051 | 0.78 | PDK1 (0.39) | PDK1PDK2PDK3PDK4CHRM2 | |
| SCHEMBL1439823 | 0.76 | AAK1 (0.36) | AAK1HDAC8HTR2CSLC6A4 | |
| SCHEMBL23579129 | 0.76 | STAT5B (0.43) | NR1H4 | |
| SCHEMBL7637435 | 0.75 | AAK1 (0.37) | AAK1 | |
| SCHEMBL23579447 | 0.74 | QPCT (0.37) | CHRM2CHRM1CHRM3HTR2CSLC6A4 | |
| SCHEMBL23247059 | 0.72 | HDAC8 (0.35) | AAK1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |