Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579269 | 0.83 | PDK1 (0.39) | CHRM2CHRM1CHRM3PDK1PDK2 | |
| SCHEMBL29973147 | 0.83 | PDK1 (0.39) | CHRM2CHRM1CHRM3PDK1PDK2 | |
| SCHEMBL23579395 | 0.79 | NPC1 (0.35) | CHRM2CHRM1CHRM3NPC1RAB9A | |
| SCHEMBL23579126 | 0.78 | CYP19A1 (0.52) | KMT2AMEN1CYP19A1THRBALDH1A1 | |
| SCHEMBL29974288 | 0.78 | CYP19A1 (0.52) | KMT2AMEN1CYP19A1THRBALDH1A1 | |
| SCHEMBL6501239 | 0.75 | PDK1 (0.41) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL1439823 | 0.75 | AAK1 (0.36) | KMT2AHDAC8STAT3HTR2CSLC6A4 | |
| SCHEMBL6493051 | 0.75 | PDK1 (0.39) | CHRM2CHRM1CHRM3PDK1PDK2 | |
| SCHEMBL23247020 | 0.74 | MAPT (0.41) | ARGAAALDH1A1MAPT | |
| SCHEMBL22897646 | 0.74 | ALDH1A1 (0.39) | KMT2AMEN1GAATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |