Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18147346 | 0.82 | HDAC1 (0.37) | AAK1CA12CA1CA2CA9 | |
| SCHEMBL29251017 | 0.82 | SSTR4 (0.38) | AAK1SSTR4SOS1MT-CO2 | |
| SCHEMBL29995099 | 0.82 | HDAC1 (0.37) | AAK1CA12CA1CA2CA9 | |
| SCHEMBL29948545 | 0.79 | NPC1 (0.40) | AAK1CA12CA1CA2CA9 | |
| SCHEMBL18146100 | 0.79 | MT-CO2 (0.35) | AAK1SSTR4SOS1MT-CO2PAX8 | |
| SCHEMBL18179676 | 0.78 | AAK1 (0.38) | AAK1SSTR4SOS1MT-CO2KDM4E | |
| SCHEMBL23579129 | 0.78 | STAT5B (0.43) | PAX8MEN1NPC1HTTRAB9A | |
| SCHEMBL6914487 | 0.77 | CYP3A4 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL5421359 | 0.77 | RAB9A (0.43) | AAK1SSTR4SOS1MT-CO2PAX8 | |
| SCHEMBL30058394 | 0.75 | HTR6 (0.41) | AAK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |