Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.43 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171386 | 0.90 | CTSS (0.56) | KLK5ACECTSSCTSKCTSB | |
| SCHEMBL7060490 | 0.90 | CTSS (0.56) | KLK5ACECTSSCTSKCTSB | |
| SCHEMBL1032021 | 0.90 | CTSS (0.56) | KLK5ACECTSSCTSKCTSB | |
| SCHEMBL21862213 | 0.89 | CTSS (0.52) | KLK5ACECTSSCTSKCTSB | |
| SCHEMBL9044348 | 0.87 | ALDH1A1 (0.47) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL29484191 | 0.86 | CTSS (0.57) | KLK5ACECTSSCTSKCTSB | |
| SCHEMBL23332639 | 0.85 | KLK5 (0.59) | KLK5ACECTSSCTSKCTSB | |
| SCHEMBL28582380 | 0.85 | KLK5 (0.59) | KLK5ACECTSSCTSKCTSB | |
| SCHEMBL11080212 | 0.84 | KLK5 (0.67) | KLK5ACECTSSCTSKCTSB | |
| SCHEMBL18206853 | 0.82 | CTSS (0.50) | KLK5ACECTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4067370-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS | Yu, Chongxi (US) | 2022-10-05 | — | — | EP | disclosed |