SCHEMBL29973367

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CXCL8	P10145	5/20	0.62

▸	GLP1R	P43220	10/20	0.61

▸	GCGR	P47871	3/20	0.61

▸	GIPR	P48546	7/20	0.60

▸	NMBR	P28336	1/20	0.59

▸	GRPR	P30550	1/20	0.59

▸	GALR2	O43603	1/20	0.58

▸	GALR1	P47211	1/20	0.58

▸	IL23R	Q5VWK5	1/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Galantide SCHEMBL31332196	0.97	IL23R (0.62)	CXCL8GLP1RGCGRGIPRNMBR
SCHEMBL30429448	0.89	GALR2 (0.62)	CXCL8GLP1RGIPRGALR2GALR1
SCHEMBL29972944	0.89	NPY1R (0.69)	GLP1RGCGRGIPRIL23R
SCHEMBL30429251	0.88	CALCA (0.62)	GLP1RGALR2GALR1
SCHEMBL30429667	0.88	NMBR (0.60)	GLP1RGCGRGIPRNMBRGRPR
SCHEMBL29972984	0.87	NPY1R (0.65)	CXCL8GLP1RGCGRGIPR
SCHEMBL31000909	0.86	CXCL8 (0.64)	CXCL8GLP1RGCGRIL23R
SCHEMBL29370578	0.86	NPY1R (0.67)	GLP1RGCGRGIPRIL23R
SCHEMBL30973903	0.86	NPY1R (0.66)	GLP1RGCGRGIPRIL23R
SCHEMBL31000914	0.86	CXCL8 (0.62)	CXCL8GLP1RGCGRGIPRIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4067370-A1	HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS	Yu, Chongxi (US)	2022-10-05	—	—	EP	disclosed