Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 4/20 | 0.51 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31230203 | 0.95 | OPRM1 (0.60) | OPRM1OPRD1OPRK1CTSBBACE1 | |
| SCHEMBL29678374 | 0.87 | OPRM1 (0.52) | OPRM1OPRD1OPRK1CTSB | |
| SCHEMBL29678509 | 0.86 | NPY4R (0.60) | — | |
| SCHEMBL29569383 | 0.85 | OPRM1 (0.57) | OPRM1OPRD1OPRK1CTSB | |
| SCHEMBL30610768 | 0.81 | BACE1 (0.56) | BACE1BACE2 | |
| SCHEMBL29406603 | 0.81 | CTSB (0.54) | OPRM1OPRD1OPRK1CTSBBACE1 | |
| SCHEMBL29568486 | 0.81 | OPRM1 (0.57) | OPRM1OPRD1OPRK1CTSB | |
| SCHEMBL30799632 | 0.81 | OPRD1 (0.65) | OPRM1OPRD1OPRK1CTSB | |
| SCHEMBL30974266 | 0.81 | TFPI (0.55) | OPRM1OPRD1OPRK1CTSBBACE1 | |
| SCHEMBL30532205 | 0.80 | FURIN (0.49) | CTSBBACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4067370-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS | Yu, Chongxi (US) | 2022-10-05 | — | — | EP | disclosed |