Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525847 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KITBRAFTP53MAPK1 | |
| SCHEMBL1525952 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KITBRAFTP53MAPK1 | |
| SCHEMBL1499525 | 0.87 | MEN1 (0.50) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL1525787 | 0.84 | TP53 (0.70) | ALDH1A1KITBRAFTP53MAPK1 | |
| SCHEMBL1525960 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TP53MAPK1KDM4EMEN1 | |
| SCHEMBL1525806 | 0.81 | TP53 (0.54) | ALDH1A1KITBRAFTP53MAPK1 | |
| SCHEMBL1499600 | 0.79 | TSHR (0.56) | ALDH1A1KITBRAFMAPK1TSHR | |
| SCHEMBL1499550 | 0.78 | TSHR (0.58) | ALDH1A1MAPK1TSHRKDM4EMEN1 | |
| SCHEMBL1499660 | 0.76 | KDR (0.53) | KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL5551707 | 0.76 | SOD1 (0.53) | ALDH1A1MEN1KMT2AL3MBTL1QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536691-B1 | CHEMICAL MOLECULES THAT INHIBIT THE SPLICING MECHANISM FOR TREATING DISEASES RESULTING FROM SPLICING ANOMALIES | CENTRE NAT RECH SCIENT (FR) | 2022-10-05 | — | — | EP | disclosed |