Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495035 | 0.82 | SOD1 (0.67) | SOD1SMN1; SMN2QPCTNPC1RAB9A | |
| SCHEMBL18457438 | 0.79 | QPCT (0.56) | SOD1TBXAS1QPCTNPC1RAB9A | |
| SCHEMBL29973771 | 0.76 | ALDH1A1 (0.54) | QPCTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL1525847 | 0.76 | ALDH1A1 (0.54) | QPCTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5903394 | 0.75 | NPC1 (0.55) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL4138098 | 0.75 | SOD1 (0.54) | SOD1QPCTNPC1RAB9AATM | |
| SCHEMBL1499525 | 0.75 | MEN1 (0.50) | SOD1SMN1; SMN2QPCTMEN1KMT2A | |
| SCHEMBL2539814 | 0.75 | SOD1 (0.57) | SOD1SMN1; SMN2TBXAS1QPCTNPC1 | |
| SCHEMBL27418532 | 0.75 | HMOX1 (0.61) | SOD1TBXAS1QPCTNPC1RAB9A | |
| SCHEMBL9706477 | 0.74 | MEN1 (0.58) | SOD1SMN1; SMN2TBXAS1QPCTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1830858-A2 | 3, 6-BICYCLOLIDES | Enanta Pharmaceuticals, Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006063039-A2 | 3, 6-BICYCLOLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |