Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.46 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.45 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.45 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.45 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654368 | 0.82 | ADRA2A (0.48) | CHRM4LRRK2SLC6A3 | |
| SCHEMBL19877102 | 0.82 | CHRM4 (0.59) | ADRB2NCF1LMNACYP1A2CYP3A4 | |
| SCHEMBL31054115 | 0.79 | LRRK2 (0.41) | ADRB2NCF1LMNACYP1A2CYP3A4 | |
| SCHEMBL13354913 | 0.78 | NCF1 (0.54) | ADRB2NCF1CYP1A2CYP3A4HPGD | |
| Hydrochloric Acid SCHEMBL30521639 | 0.78 | LRRK2 (0.40) | LMNACYP1A2CYP3A4KDM4EMEN1 | |
| SCHEMBL2709925 | 0.77 | HTR2C (0.52) | ADRB2NCF1LMNACYP1A2CYP3A4 | |
| SCHEMBL28284099 | 0.75 | CHRM4 (0.48) | CHRM4LRRK2 | |
| SCHEMBL15190644 | 0.75 | MELK (0.64) | CHRM4LRRK2 | |
| SCHEMBL13322696 | 0.75 | NCF1 (0.50) | ADRB2NCF1HPGDPDE10A | |
| SCHEMBL18600014 | 0.75 | NCF1 (0.50) | ADRB2NCF1HPGDPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329888-A1 | 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | Amgen Inc. (US) | 2024-03-06 | — | — | EP | claimed |
| WO-2022232332-A1 | 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | AMGEN INC. (US) | 2022-11-03 | — | — | WO | claimed |
| CN-118510785-B | Nitrogen-containing heterocyclic compound and application thereof | 凌科药业(杭州)有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-118510785-A | Nitrogen-containing heterocyclic compound and application thereof | 凌科药业(杭州)有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-113637005-B | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-4329888-A1 | 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | Amgen Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022232332-A1 | 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | AMGEN INC. (US) | 2022-11-03 | — | — | WO | disclosed |