Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | AOC2 | O75106 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27730852 | 0.85 | HPGD (0.61) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL860446 | 0.83 | HPGD (0.59) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL5847146 | 0.83 | HPGD (0.64) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL29974170 | 0.83 | HPGD (0.59) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL5109501 | 0.83 | HPGD (0.64) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL1519327 | 0.83 | HPGD (0.64) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL2458533 | 0.82 | HDAC3 (0.45) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL5722756 | 0.82 | HDAC3 (0.45) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL16429453 | 0.82 | HDAC3 (0.45) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL3885950 | 0.82 | HPGD (0.44) | HPGDTSHRNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428370-B2 | Haloallylamine dual amine oxidase inhibitors | SYNTARA LIMITED (AU) | 2025-09-30 | — | — | US | disclosed |
| CN-115916337-B | Halogenated allylamine bis amine oxidase inhibitors | 法玛西斯有限公司 | 2025-04-15 | — | — | CN | disclosed |
| US-20230257342-A1 | HALOALLYLAMINE DUAL AMINE OXIDASE INHIBITORS | PHARMAXIS LTD. (AU) | 2023-08-17 | — | — | US | disclosed |
| US-20230257342-A1 | HALOALLYLAMINE DUAL AMINE OXIDASE INHIBITORS | PHARMAXIS LTD. (AU) | 2023-08-17 | — | — | US | disclosed |
| US-20230257342-A1 | HALOALLYLAMINE DUAL AMINE OXIDASE INHIBITORS | PHARMAXIS LTD. (AU) | 2023-08-17 | — | — | US | disclosed |
| EP-4171740-A1 | HALOALLYLAMINE DUAL AMINE OXIDASE INHIBITORS | Pharmaxis Ltd. (AU) | 2023-05-03 | — | — | EP | disclosed |
| WO-2021258159-A1 | HALOALLYLAMINE DUAL AMINE OXIDASE INHIBITORS | PHARMAXIS LTD. (AU) | 2021-12-30 | — | — | WO | disclosed |
| US-20150073177-A1 | METHOD FOR INHIBITING TRYPANOSOMA CRUZI | HOWARD UNIVERRSITY (US) | 2015-03-12 | — | — | US | disclosed |
| EP-2519103-B1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER IP GMBH (DE) | 2014-08-13 | — | — | EP | disclosed |
| US-8796463-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2014-08-05 | — | — | US | disclosed |
| US-20080262224-A1 | Method of Preparation of Benzofuran-2-Carboxylic Acid -Amide | SMITHKLINE BEECHAM CORPORATION | 2008-10-23 | — | — | US | disclosed |
| EP-1947093-A1 | Substituted morpholine and thiomorpholine derivatives | H. Lundbeck A/S (DK) | 2008-07-23 | — | — | EP | disclosed |
| EP-1727809-B1 | SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2008-06-11 | — | — | EP | disclosed |
| EP-1727809-A1 | SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| US-20060167248-A1 | Substituted morpholine and thiomorpholine derivatives | H. LUNDBECK A/S (DK) | 2006-07-27 | — | — | US | disclosed |
| WO-2005087754-A1 | SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | disclosed |
| WO-2005019168-A2 | FLUORINATED LYSINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20050043292-A1 | Fluorinated lysine derivatives as dipeptidyl peptidase IV inhibitors | PFIZER INC | 2005-02-24 | — | — | US | disclosed |
| US-4279910-A | Quinazoline therapeutic agents | PFIZER INC. (US) | 1981-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043292-A1 | Fluorinated lysine derivatives as dipeptidyl peptidase IV inhibitors | DPP4, DPP7, ALPI | HPGD 3954/4885TSHR 1448/4885NFKB1 2529/4885 |
| US-20060167248-A1 | Substituted morpholine and thiomorpholine derivatives | OPRM1, OPRK1, OPRD1 | HPGD 2427/4885TSHR 155/4885NFKB1 3880/4885 |
| US-20230257342-A1 | HALOALLYLAMINE DUAL AMINE OXIDASE INHIBITORS | AOC2, AOC3, AOC1 | HPGD 765/4885TSHR 2376/4885NFKB1 3241/4885 |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | GHSR, GIPR, GPR119 | HPGD 231/4885TSHR 348/4885NFKB1 2068/4885 |
| US-20080262224-A1 | Method of Preparation of Benzofuran-2-Carboxylic Acid -Amide | ACMSD, CPS1, BCAT2 | HPGD 2543/4885TSHR 3582/4885NFKB1 843/4885 |
| US-12428370-B2 | Haloallylamine dual amine oxidase inhibitors | AOC2, AOC3, AOC1 | HPGD 765/4885TSHR 2376/4885NFKB1 3241/4885 |
| US-20150073177-A1 | METHOD FOR INHIBITING TRYPANOSOMA CRUZI | PCNA, NQO1, NQO2 | HPGD 507/4885TSHR 2579/4885NFKB1 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.