Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129634 | 0.77 | NPC1 (0.40) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL21154463 | 0.73 | JAK2 (0.55) | ALDH1A1TSHRRAB9AMEN1KMT2A | |
| SCHEMBL3168953 | 0.72 | ALDH1A1 (0.45) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL16480432 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL4473144 | 0.71 | NPC1 (0.45) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL146981 | 0.71 | ALDH1A1 (0.71) | ALDH1A1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL7195074 | 0.69 | PDE10A (0.45) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL10921639 | 0.69 | PDE10A (0.45) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL4059196 | 0.68 | ALDH1A1 (0.53) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL2668952 | 0.66 | PDE10A (0.47) | ALDH1A1TSHRNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397425-A | Treatment of cognitive disorders using trapidil | 希诺皮亚生物科学公司 | 2022-11-25 | — | — | CN | disclosed |