SCHEMBL2997466

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2992096	0.90	CYP3A4 (0.41)	TP53MAPTCNR1PDE4DPDE7A
	SCHEMBL13211536	0.90	PTGDR (0.36)	TP53POLBMAPTBLMRXFP1
	SCHEMBL425968	0.86	NR4A2 (0.45)	ALDH1A1KDM4ERAB9A
	SCHEMBL13211498	0.83	POLB (0.39)	TP53POLBMAPTBLMRXFP1
	SCHEMBL13211487	0.83	ALDH1A1 (0.39)	TP53POLBMAPTBLMRXFP1
	SCHEMBL27642142	0.83	FABP4 (0.35)	TP53POLBMAPTBLMRXFP1
	SCHEMBL13211483	0.83	FABP4 (0.38)	POLBALDH1A1KDM4EFABP4USP2
	SCHEMBL5234576	0.83	SCN9A (0.36)	TP53POLBMAPTBLMRXFP1
	SCHEMBL2992060	0.83	FABP4 (0.34)	TP53POLBMAPTBLMRXFP1
	SCHEMBL2998608	0.82	CNR1 (0.37)	POLBCNR1ALDH1A1KDM4EFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.