Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579132 | 1.00 | ADORA1 (0.44) | ADORA1MEN1CASP3BLMKMT2A | |
| SCHEMBL904407 | 0.89 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ADORA2AHPGDCYP3A4 | |
| SCHEMBL28374374 | 0.79 | ALDH1A1 (0.50) | MEN1BLMKMT2ANCOA1NCOA3 | |
| SCHEMBL16178332 | 0.77 | HSD17B10 (0.48) | ADORA1MEN1BLMKMT2AALDH1A1 | |
| SCHEMBL29638163 | 0.77 | HSD17B10 (0.48) | ADORA1MEN1BLMKMT2AALDH1A1 | |
| SCHEMBL28130162 | 0.77 | HSD17B10 (0.48) | ADORA1MEN1BLMKMT2AALDH1A1 | |
| SCHEMBL28293323 | 0.76 | ADORA1 (0.49) | ADORA1MEN1CASP3BLMKMT2A | |
| SCHEMBL10608496 | 0.76 | HSD17B10 (0.48) | ADORA1ALDH1A1HSD17B10ADORA2AHPGD | |
| SCHEMBL28897414 | 0.75 | HSD17B10 (0.48) | ADORA1ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL845162 | 0.74 | HSD17B10 (0.52) | ADORA1ALDH1A1HSD17B10ADORA2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |