Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974840 | 0.86 | HTR6 (0.41) | GRIN2BTSHRPLA2G7RIPK3MAPK14 | |
| SCHEMBL29975240 | 0.85 | MAPT (0.41) | GRIN2BMAPTPLA2G7RIPK3SCN9A | |
| SCHEMBL25043409 | 0.83 | RIPK3 (0.52) | RIPK3FAAHMAPK14 | |
| SCHEMBL23410436 | 0.82 | GRIA1 (0.47) | GRIN2BTSHR | |
| SCHEMBL18042004 | 0.73 | TGFBR1 (0.53) | LMNAMAPTHTTTSHRFAAH | |
| SCHEMBL25044591 | 0.72 | RIPK3 (0.52) | RIPK3MAPK14 | |
| SCHEMBL30232366 | 0.72 | RIPK3 (0.49) | RIPK3MAPK14 | |
| SCHEMBL15006965 | 0.71 | LMNA (0.42) | GRIN2BLMNATSHRPLA2G7 | |
| SCHEMBL30232556 | 0.71 | RIPK3 (0.50) | MAPTRIPK3MAPK14 | |
| SCHEMBL23410296 | 0.70 | GRIA1 (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151256-A | Novel compounds for the treatment of diseases associated with DUX expression | FACIO知识产权有限公司 | 2022-10-04 | — | — | CN | disclosed |