Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187571 | 0.72 | HSD11B1 (0.48) | HSD11B1ALDH1A1POLBKDM4ENISCH | |
| SCHEMBL29974695 | 0.72 | KDM4E (0.39) | ALDH1A1KDM4EGLAGAA | |
| SCHEMBL23579398 | 0.72 | KDM4E (0.39) | ALDH1A1KDM4EGLAGAA | |
| SCHEMBL21187570 | 0.71 | NISCH (0.42) | HSD11B1POLBKDM4ENISCHCLK1 | |
| SCHEMBL109905 | 0.70 | — | — | |
| SCHEMBL31484033 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL8873914 | 0.68 | TSHR (0.58) | ALDH1A1POLBKDM4ENISCHALOX15 | |
| SCHEMBL20698133 | 0.68 | POLB (0.52) | HSD11B1POLBNISCHNOTUMPDE2A | |
| SCHEMBL17514609 | 0.67 | NISCH (0.43) | HSD11B1ALDH1A1KDM4ENISCHGRM2 | |
| SCHEMBL29974505 | 0.67 | ALDH1A1 (0.40) | ALDH1A1KDM4EALOX15HTR1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335046-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |