Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579398 | 1.00 | KDM4E (0.39) | KDM4ESRCBRAFKDRUSP7 | |
| SCHEMBL1664825 | 0.86 | KIF11 (0.48) | KDM4EUSP7ALDH1A1ACHECYP3A4 | |
| SCHEMBL29974505 | 0.82 | ALDH1A1 (0.40) | KDM4EUSP7ALDH1A1ACHECYP1A2 | |
| SCHEMBL29620304 | 0.72 | KIF11 (0.36) | KDM4EUSP7ALDH1A1CYP3A4HPGD | |
| SCHEMBL6313808 | 0.72 | KIF11 (0.36) | KDM4EUSP7ALDH1A1CYP3A4HPGD | |
| SCHEMBL29974866 | 0.72 | HSD11B1 (0.41) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL29974481 | 0.72 | TRPA1 (0.35) | KDM4ESRCBRAFKDRALDH1A1 | |
| SCHEMBL30234670 | 0.72 | CYP3A4 (0.43) | KDM4ESRCBRAFKDRALDH1A1 | |
| SCHEMBL29013658 | 0.70 | KIF11 (0.60) | KIF11 | |
| SCHEMBL30972581 | 0.68 | HSD17B10 (0.44) | KDM4EUSP7ALDH1A1ACHECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |