Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 5/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22557297 | 1.00 | PIK3CD (0.49) | PIK3CDCA2CHKANOS3NOS2 | |
| SCHEMBL600673 | 0.83 | PIK3CD (0.49) | PIK3CDCA2CHKANOS3NOS2 | |
| Hydrochloric Acid SCHEMBL601414 | 0.82 | PIK3CD (0.47) | PIK3CDCA2CHKANOS3NOS2 | |
| SCHEMBL16712832 | 0.80 | CA2 (0.45) | PIK3CDCA2CHKANOS3NOS2 | |
| SCHEMBL30433748 | 0.78 | PIK3R1 (0.38) | PIK3CDMBOAT4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1471015 | 0.78 | PIK3R1 (0.38) | PIK3CDMBOAT4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20772336 | 0.77 | PIK3CD (0.42) | PIK3CDCA2CHKANOS3NOS2 | |
| SCHEMBL20985352 | 0.76 | NOS3 (0.38) | PIK3CDNOS3NOS2KDM4EPIK3CB | |
| SCHEMBL30940520 | 0.76 | NOS3 (0.38) | PIK3CDNOS3NOS2KDM4EPIK3CB | |
| SCHEMBL24858337 | 0.75 | NOS3 (0.56) | PIK3CDCA2CHKANOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113939509-B | Novel heteroaryl substituted aminoalkylazole compounds as pesticides | 拜耳动物保健有限责任公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118632836-A | Novel aminobenzene derivative having cancer cell growth inhibitory effect and preventive or therapeutic pharmaceutical composition containing the same as active ingredient | 株式会社大熊制药 | 2024-09-10 | — | — | CN | disclosed |
| EP-4329757-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117561063-A | Heterocyclic compounds and methods of use | 安进公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2022232331-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-11-03 | — | — | WO | disclosed |