Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994979 | 0.79 | ALDH1A1 (0.44) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL15974565 | 0.79 | HPGD (0.50) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL486988 | 0.77 | HPGD (0.47) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2997519 | 0.76 | HPGD (0.46) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2994977 | 0.75 | ALDH1A1 (0.41) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL31332733 | 0.74 | HPGD (0.45) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20825485 | 0.74 | HPGD (0.45) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2999551 | 0.74 | ALDH1A1 (0.46) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6766423 | 0.73 | HPGD (0.41) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6766939 | 0.72 | ALDH1A1 (0.47) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |