SCHEMBL31332733

SCHEMBL31332733

COC(=O)C(F)C1CC2CCC1C2

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.45
LMNA P02545 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 4/20 0.43
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
POLB P06746 2/20 0.40
SLC6A3 Q01959 1/20 0.38
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2997519 0.84 HPGD (0.46) HPGDLMNASMN1; SMN2ALDH1A1KMT2A
SCHEMBL486988 0.82 HPGD (0.47) HPGDLMNASMN1; SMN2ALDH1A1KMT2A
SCHEMBL15974565 0.81 HPGD (0.50) HPGDLMNASMN1; SMN2ALDH1A1KMT2A
SCHEMBL20825485 0.79 HPGD (0.45) HPGDLMNASMN1; SMN2ALDH1A1KMT2A
SCHEMBL31332785 0.78 HPGD (0.42) HPGDLMNASMN1; SMN2ALDH1A1KMT2A
SCHEMBL2997520 0.74 HPGD (0.44) HPGDLMNASMN1; SMN2ALDH1A1KMT2A
SCHEMBL2999547 0.73 ALDH1A1 (0.50) HPGDLMNASMN1; SMN2ALDH1A1KMT2A
SCHEMBL6854602 0.73 ATM (0.43) HPGDLMNASMN1; SMN2ALDH1A1KMT2A
SCHEMBL22552890 0.72 ALDH1A1 (0.41) HPGDLMNASMN1; SMN2ALDH1A1KMT2A
SCHEMBL25075854 0.69 LMNA (0.36) HPGDLMNASMN1; SMN2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709708-A1 NOVEL CARBOXAMIDE DERIVATIVES ANGELINI PHARMA S.P.A. (IT) 2026-03-18 EP disclosed
WO-2024233603-A1 NOVEL CARBOXAMIDE DERIVATIVES ICAGEN, LLC (US) 2024-11-14 WO disclosed