SCHEMBL2997519

SCHEMBL2997519

COC(=O)C(C(=O)OC)C(C1CC2CCC1C2)C1CC2CCC1C2

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 1/20 0.46
ALDH1A1 P00352 4/20 0.44
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
POLB P06746 2/20 0.40
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2999547 0.85 ALDH1A1 (0.50) HPGDSMN1; SMN2LMNAALDH1A1KMT2A
SCHEMBL31332733 0.84 HPGD (0.45) HPGDSMN1; SMN2LMNAALDH1A1KMT2A
SCHEMBL486988 0.84 HPGD (0.47) HPGDSMN1; SMN2LMNAALDH1A1KMT2A
SCHEMBL15974565 0.82 HPGD (0.50) HPGDSMN1; SMN2LMNAALDH1A1KMT2A
SCHEMBL20825485 0.81 HPGD (0.45) HPGDSMN1; SMN2LMNAALDH1A1KMT2A
SCHEMBL22552890 0.77 ALDH1A1 (0.41) HPGDSMN1; SMN2LMNAALDH1A1KMT2A
SCHEMBL2997520 0.76 HPGD (0.44) HPGDSMN1; SMN2LMNAALDH1A1KMT2A
SCHEMBL6854602 0.74 ATM (0.43) HPGDSMN1; SMN2LMNAALDH1A1KMT2A
SCHEMBL25075854 0.70 LMNA (0.36) HPGDSMN1; SMN2LMNAALDH1A1KMT2A
SCHEMBL3000074 0.70 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed