Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.60 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.60 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.60 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176762 | 0.85 | KMT2A (0.62) | KMT2AMEN1ALDH1A1TSHRABCC9 | |
| SCHEMBL1869837 | 0.83 | TGM2 (0.63) | KMT2AMEN1ALDH1A1TSHRABCC9 | |
| SCHEMBL396051 | 0.83 | MEN1 (0.57) | KMT2AMEN1ALDH1A1TSHRABCC9 | |
| SCHEMBL15203492 | 0.81 | MEN1 (0.58) | KMT2AMEN1ALDH1A1TSHRABCC9 | |
| SCHEMBL31195242 | 0.81 | PRMT1 (0.64) | KMT2AMEN1ALDH1A1TSHRABCC9 | |
| SCHEMBL15203493 | 0.81 | CA1 (0.62) | KMT2AMEN1ALDH1A1TSHRABCC9 | |
| SCHEMBL9096041 | 0.80 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1TSHRABCC9 | |
| SCHEMBL4163070 | 0.79 | MEN1 (0.59) | KMT2AMEN1ALDH1A1TSHRABCC9 | |
| SCHEMBL14283242 | 0.78 | LMNA (0.66) | KMT2AMEN1ALDH1A1TSHRABCC9 | |
| SCHEMBL6951902 | 0.76 | LMNA (0.63) | KMT2AMEN1ALDH1A1TSHRABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | SIGA TECHNOLOGIES, INC. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | EIF2AK2, HAVCR2, SNRPE | KMT2A 3347/4885MEN1 3401/4885ALDH1A1 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.